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di-tert-butyl dicarbonate CAS 24424-99-5

di-tert-butyl dicarbonate CAS 24424-99-5

Di-tert-butyl dicarbonate with CAS 24424-99-5 is transparent crystal or liquid, and it is used as medicine and organic synthesis intermediates. Jinan Great Chemical Industry Co., Ltd is a professional manufacturer and supplier of di-tert-butyl dicarbonate. To know more about di-tert-butyl dicarbonate, please don’t hesitate to contact sale001@chemgreat.com .

Description

Description

Di-tert-butyl dicarbonate (Diboc) is a novel amino-protecting agent used in organic synthesis to introduce a tert-butoxycarbonyl (BOC) protectant, especially for amino-protection of amino acids. Widely used in the synthesis of pharmaceuticals, protein and peptide synthesis, biochemistry, food, cosmetics and other products. The finished product is a colorless crystal or a colorless liquid, and is dissolved in an organic solvent such as tetrahydrofuran, n-hexane, benzene or chloroform, and slightly soluble in water.

Parameter

di-tert-butyl dicarbonate 

Chemical   name

di-tert-butyl dicarbonate

Another   name

BOC-anhydride, DBDC , EINECS 246-240-1

Molecular   Formular

C10H18O5

Molecular   Weight

218.25

Cas   No.

24424-99-5

EINECS   No.

246-240-1

Appearance

Transparent crystal or liquid

Purity

99%

Density

1.1±0.1g/cm3

Melting   point

23 ℃ (lit.)

Boiling   point

235.8±0.0   °C at 760 mmHg

Package

50kg/steel   drum

Hazard   Class

6.1

UN   No.

UN   2929 6.1/PG 1

Storage   Conditions

Cool,dry   and hermetic place

Description of use

Pharmaceutical and organic synthesis intermediates are important amino protecting agents for the synthesis of pharmaceutical and agrochemical products.

Used as an intermediate in medicine and organic synthesis, it is an important amino protecting agent for the synthesis of pharmaceutical and agrochemical products.

In organic chemical reactions, tert-butoxycarbonylation reagents, which are often used as substrates for amines, phenols, thiols, amides, lactams, carbamates, etc., have a fast reaction rate and a relatively high yield. Tert-butoxycarbonylation (protection of functional groups); Because of its poor stability, the acid halide reagent is widely used as a protecting group for amino groups under acidic conditions (eg, hydrochloric acid, trifluoroacetic acid, etc.) ) can be taken off. Fatty amines, alicyclic amines, aromatic amines, and heterocyclic amines are all capable of reacting with (Boc).

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