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Capecitabine CAS 154361-50-9;158798-73-3;5-Deoxy-5-fluoro-N-[(pentyloxy)carbonyl]cytidine

Capecitabine CAS 154361-50-9;158798-73-3;5-Deoxy-5-fluoro-N-[(pentyloxy)carbonyl]cytidine

Capecitabine is anticancer drugs. If you are looking for Capecitabine,Jinan Great Chemical Industry Co.,Ltd is your good option. We have many years’ experience in manufacturing and supplying Capecitabine.For more information,please feel free to contact sale001@chemgreat.com.

Description

Description

Capecitabine is rapidly absorbed by the intestinal mucosa after oral administration, and then converted into an inactive intermediate 5'-deoxy-5' fluorocytidine in the liver by carboxylesterase, followed by cytidine removal from liver and tumor tissues. The action of the aminoase is converted to 5'-deoxy-5' fluorouridine and finally catalyzed by thymidine phosphorylase to fluorouracil (5-FU) in tumor tissues.

Parameter

Chemical name

Capecitabine

Molecular Structure

图片28.jpg

Molecular Formular

C9H12FN3O4

Molecular Weight

245.2077

Cas No.

154361-50-9;158798-73-3

Appearance

Colorless solid

Purity

>=98%

Melting point

110-121°C

Boiling point

437.874°C at 760 mmHg

Package

10KG/DRUM

Storage Conditions

Store in original container in a cool dark place

Application

Anticancer drugs

Adverse reactions

Can have diarrhea, nausea, vomiting, gastritis. Hand and foot syndrome occurs in almost half of patients, manifested as: numbness, dullness, paresthesia, tingling, painlessness and pain, skin swelling and erythema, blisters or severe pain. Dermatitis and hair loss are more common. Often fatigue, mucositis, fever, weakness, lethargy, as well as headache, taste disorders, dizziness, insomnia, neutropenia, anemia, dehydration.

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